What is the antibody-drug conjugates market growth?
Antibody Drug Conjugate Market Analysis
The global antibody drug conjugate market is projected to witness
a stupendous growth at a notable 16.70% CAGR over the predicted years. ADCs are
made of three parts- first a specific antibody for binding, an antigen that has
limited expression on the normal cells, second a cytotoxic agent to kill target
cancer cells and third a chemical linker to attach the cytotoxic agent to the
antibody. This is how antibody drug conjugates work. They are the new age of therapeutic
agents. One of the key advantages of antibody drug conjugates is that this will
help in bringing together the finest characteristics of both antibodies as well
as the chemotherapy’s cytotoxic potential.
There are many factors that is fuelling the growth of the antibody drug
conjugate market. The different antibody drug conjugate market
trends and factors in this market according to an analysis performed by Market
Research Future (MRFR) include increasing prevalence of cancer, advancement in
medical technology, increased investment in R & D, efficacy of ADC in
treating diseases, rising collaboration amid biotechnology and
biopharmaceuticals and research institutes, preclinical research, growing
geriatric population and rise in obese population. On the contrary, the soaring
cost related to the procedure may hamper the growth of the antibody drug
conjugate market.
Regional Analysis
Based on region, the antibody drug conjugate market covers growth
opportunities and latest trends across North America, Europe, Asia Pacific and
Middle East and Africa. Of these, North America is expected to accrue maximum
share in the market due to advancement in manufacturing techniques,
technological innovation and contribution of nanotechnology to create ADC. The
U.S. FDA has given approval to only three ADC. The antibody drug conjugate
market in Europe will have the second largest share followed by the APAC
region. APAC is an emerging market and the factors that are driving the growth
of the market include increasing government initiatives. A good number of
products are under the pipeline and such developments are performed under
license agreements.
Market Segmentation
As per MRFR report, the global antibody drug conjugate market is
segmented on the basis of type, product, technology, application and end-user.
Based on type, it is segmented into drug/toxin, linker, monoclonal
antibodies and others. Of these, the antibody drug conjugate linker is expected
to have the maximum antibody drug conjugate
market share.
Based on application, the antibody drug conjugate market is segmented
into lymphoma, multiple myeloma, solid tumors, skin cancer, breast cancer,
colon cancer, lung cancer, glioblastoma, ovary cancer, pancreas cancer, kidney
cancer, prostate cancer and leukemia. Leukemia is further segmented into
Chronic Lymphocytic Leukemia (CLL), Acute Lymphocytic Leukemia (ALL), Chronic
Myeloid Leukemia (CML), and Acute Myeloid Leukemia (AML). Of these, breast cancer
had the maximum share owing to its increasing prevalence.
Based on product, it is segmented into Kadcyla, Adcertis and others.
Based on technology, the antibody drug conjugate market is segmented
into Immunomedics technology, Seattle Genetics technology, ImmunoGen technology
and others.
Based on end-user, it is segmented into biopharmaceutical companies,
biotechnology companies, academic research institutes, specialized cancer and
others.
Key Players
Leading players profiled in the antibody drug conjugate market include
Synthon (U.S.), Mersana Therapeutics (U.S.), Oxford BioTherapeutics (U.S.),
Heidelberg Pharma (Germany), Progenics Pharmaceuticals (U.S.), Astellas
Pharma/Agensys (Japan), Bayer HealthCare (Germany), Agensys, Inc. (U.S.),
Concortis Biotherapeutics (U.S.), Genentech (U.S.), AbbVie Inc. (U.S.),
Millennium Pharmaceuticals (U.S.), Celldex Therapeutics (U.S.), Pfizer Inc.
(U.S.), Immunomedics (U.S.), Antikor (U.K.), Roche Holding AG (Switzerland),
ImmunoGen, Inc. (U.S.), and Seattle Genetics (U.S.).
Feb 2019- The Food and Drug Administration (FDA) has granted priority
review to ADC (antibody drug conjugate) for diffusing large B-Cell Lymphoma.
The chief medical officer of global product development is working with the
Food and Drug Administration for bringing this vital novel option to patients
having this aggressive ailment as fast as possible. The FDA is most likely to
come up with the decision by August 19, 2019.
Jan 2019- Daiichi Sankyo has come up with a late-stage study of ADC to
treat patients having low expressing HER2 metastatic/unresectable breast
cancer.
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